Colorectal cancer in Iran: Epidemiology and morphology trends

Authors

  • Hosein Rafiemanesh Students' Research Committee, School of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • Reza Pakzad Students' Research Committee, Ilam University of Medical Sciences, Ilam, Iran
  • Mehdi Abedi School of Medicine, Islamic Azad University Tehran Medical Branch, Tehran, Iran
  • Yones Kor Department of Elder Nursing, School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran
  • Jalal Moludi Department of Biochemistry and Diet Therapy, Faculty of Nutrition, Nutrition Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
  • Farhad Towhidi Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran
  • Behnam Reza Makhsosi Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran
  • Hamid Salehiniya Zabol University of Medical Sciences, Zabol, Iran; Tehran University of Medical Sciences, Tehran, Iran

DOI:

https://doi.org/10.17179/excli2016-346

Keywords:

colorectal cancer, epidemiology, morphology, trend, Iran

Abstract

Colorectal cancer is one of the most prevalent cancers in different countries, including Iran. No comprehensive study has been done in the country for colorectal cancer, but information on the incidence and trends is essential to planning. This study aimed to evaluate the occurrence and morphology of colorectal cancer and its trend in Iran. This study was conducted using data from the national cancer registry system in Iran from 2003-2008. We used joinpoint regression analysis for assessing incidence time trends and morphology change percentage. Of all cases of colorectal cancer, 61.83 % were colon cancer, 27.54 % rectal cancer, 7.46 % rectosigmoid cancer, and 3.10 anal cancer. The most common histological types with the frequencies of 80.85 % was related to adenocarcinoma, NOS. The Annual percentage changes (APC) in ASIR for colorectal cancer significantly increased in both men and women. APC in ASIR was 13.7 (CI: 10.5-17.1) in women and 16.4 (CI: 12.4-20.5) in men. APC of adenocarcinoma in villous adenoma showed significant declining trend (p<0.05), while APC of adenocarcinoma, NOS had a constant trend. The incidence of the cancer in recent years has increased in Iran because of changes in lifestyle and diet. Therefore, further studies are necessary to detect the cause of this cancer and perform preventive measures.

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Published

2016-11-28

How to Cite

Rafiemanesh, H., Pakzad, R., Abedi, M., Kor, Y., Moludi, J., Towhidi, F., … Salehiniya, H. (2016). Colorectal cancer in Iran: Epidemiology and morphology trends. EXCLI Journal, 15, 738–744. https://doi.org/10.17179/excli2016-346

Issue

Vol. 15 (2016)

Section

Original articles

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