The role of N(6)-methyladenosine (m6a) modification in cancer

recent advances and future directions

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DOI:

https://doi.org/10.17179/excli2024-7935

Keywords:

N(6)-methyladenosine (m6A), writers, erasers, readers, cancer

Abstract

N(6)-methyladenosine (m6A) modification is the most abundant and prevalent internal modification in eukaryotic mRNAs. The role of m6A modification in cancer has become a hot research topic in recent years and has been widely explored. m6A modifications have been shown to regulate cancer occurrence and progression by modulating different target molecules. This paper reviews the recent research progress of m6A modifications in cancer and provides an outlook on future research directions, especially the development of molecularly targeted drugs.

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Published

2025-01-15

How to Cite

Xie, X., Fang, Z., Zhang, H., Wang, Z., Li, J., Jia, Y., … Li, F. (2025). The role of N(6)-methyladenosine (m6a) modification in cancer: recent advances and future directions. EXCLI Journal, 24, 113–150. https://doi.org/10.17179/excli2024-7935

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Review articles

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